This disease advisory describes the history, known host range, clinical signs and PCR detection methods for decapod iridescent virus 1 (DIV1). Preventative strategies are suggested. Currently known susceptible species of DIV1 include Penaeus vannamei, Macrobrachium rosenbergii, Exopalaemon carinicauda, M. nipponense, Procambarus clarkii, and Cherax quadricarinatus. Clinical signs of infected P. vannamei are not typical, including slightly reddish body, hepatopancreatic atrophy with colour fading, and empty stomach and guts.