This event, held jointly via Zoom or in person at FAO Headquarters in Rome, will bring together leading experts to delve into the topic of fish vaccination and new developments regarding shrimp vaccination as a vital biosecurity strategy. Current knowledge will be reviewed, examining obstacles, and uncovering opportunities for vaccine development. Bridging theory with actionable practice, the seminar aims to foster informed decision-making, discussing the potential of vaccination and addressing associated challenges. Building upon the success of the Tilapia Health webinar held in December 2021 and Tilapia health: quo vadis, this conference will be a continuation of impactful discussions, promising a dynamic and enriching experience for all participants.