This video by Chokanan Prompichai, NACA, presents two promising innovations aimed at reducing antimicrobial use (AMU) in aquaculture, showcased as part of Thailand’s National Innovation and Investment Plan (NIIP) and via the IDRC-funded InnoVet-AMR 2.0 Project. NanoVac, developed by AIT, uses nanobubbles to deliver vaccines to tilapia, while ShrimpGuard, developed by BIOTEC and KU, is a bacteriophage-based solution for managing shrimp diseases. Both technologies offer potential to combat antimicrobial resistance (AMR) without leaving chemical residues. The presentation compares their readiness, challenges, and adoption, incorporating feedback from shrimp farmers across Thailand. It highlights the need for cost-effective, easy-to-use solutions that align with farmers' real-world needs and regulatory frameworks.